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Dr. Clemens' research focuses on infectious diseases in developing countries. His studies include evaluations of vaccines, including field evaluations and development of innovative methodological approaches; epidemiological studies, with a particular interest in enteric infections; and development of evidence-based policy for the introduction of vaccines and other interventions.
Dr. John Clemens is Professor and Vice Chairman in the Department of Epidemiology, as well as the founding director of the Center for Global Infectious Diseases. His scientific career has focused on global health and has spanned academia, the US government and international organizations. He led the team that developed the first low-cost oral vaccine against cholera, which was recently deployed in Haiti. In recognition of his work, he was awarded the Sabin Gold Medal in 2010. Dr. Clemens has published more than 300 peer-reviewed papers, and serves on the editorial boards of several international journals. He is an elected member of the American Epidemiology Society and a Fellow of both the American College of Epidemiology and the Infectious Disease Society of America. Previous positions held include chief of the Epidemiology Section of the Center for Vaccine Development of the University of Maryland, chief of the Epidemiology Branch of the National Institute of Child Health and Human Development, and Director-General of the International Vaccine Institute in Seoul.
Clemens John Evaluation of vaccines against enteric infections: a clinical and public health research agenda for developing countries.. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2011; 366(1579): 2799-805.
Ali Mohammad, Emch Michael, Park Jin Kyung, Yunus Mohammad, Clemens John Natural cholera infection-derived immunity in an endemic setting.. The Journal of infectious diseases. 2011; 204(6): 912-8.
Clemens John, Shin Sunheang, Ali Mohammad New approaches to the assessment of vaccine herd protection in clinical trials.. The Lancet infectious diseases. 2011; 11(6): 482-7.
Sur Dipika, Lopez Anna Lena, Kanungo Suman, Paisley Allison, Manna Byomkesh, Ali Mohammad, Niyogi Swapan K, Park Jin Kyung, Sarkar Banawarilal, Puri Mahesh K, Kim Deok Ryun, Deen Jacqueline L, Holmgren Jan, Carbis Rodney, Rao Raman, Nguyen Thu Van, Donner Allan, Ganguly Nirmal K, Nair G Balakrish, Bhattacharya Sujit K, Clemens John D Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial.. Lancet. 2009; 374(9702): 1694-702.
Sur Dipika, Ochiai R Leon, Bhattacharya Sujit K, Ganguly Nirmal K, Ali Mohammad, Manna Byomkesh, Dutta Shanta, Donner Allan, Kanungo Suman, Park Jin Kyung, Puri Mahesh K, Kim Deok Ryun, Dutta Dharitri, Bhaduri Barnali, Acosta Camilo J, Clemens John D A cluster-randomized effectiveness trial of Vi typhoid vaccine in India. The New England journal of medicine. 2009; 361(4): 335-44.
Ochiai R Leon, Acosta Camilo J, Danovaro-Holliday M Carolina, Baiqing Dong, Bhattacharya Sujit K, Agtini Magdarina D, Bhutta Zulfiqar A, Canh Do Gia, Ali Mohammad, Shin Seonghye, Wain John, Page Anne-Laure, Albert M John, Farrar Jeremy, Abu-Elyazeed Remon, Pang Tikki, Galindo Claudia M, von Seidlein Lorenz, Clemens John D, Clemens John D A study of typhoid fever in five Asian countries: disease burden and implications for controls.. Bulletin of the World Health Organization. 2008; 86(4): 260-8.
Lucas M, Deen JL, von Seidlein L, Wang X-Y, Ampuero J, Puri M, Ali M, Ansaruzzaman M, Amos J, Cavallier P, Guerin P, McChesney M, Mahoudeau C, Kahozi P, Chaignat C-Barreto A, Songane F, Clemens JD The effectiveness of an internationally licensed, two dose oral cholera vaccine when given in a mass vaccination campaign in Beira, Mozambique. New England Journal of Medicine. 2005; 352: 757-67.
Clemens J, Jodar L Introducing new vaccines into developing countries: obstacles, opportunities, and complexities. Nature(Medicine) 2005; 11(4 Suppl): S12-15.
Ali M, Emch M, von Seidlein L, Yunus M, Sack D, Rao M, Holmgren J, Clemens J Herd immunity conferred by killed oral cholera vaccines in Bangladesh. Lancet 2005; (366): 44-49.