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Statistical Methodology

Alexandra M. Binder

My research has focused on the potential of epigenetic epidemiology to elucidate the pathway by which adult disease susceptibility is influenced by environmental stimuli during critical periods of plasticity in fetal development. To explore multiple facets of this regulatory network, I have worked to develop expertise in the preprocessing and analysis of sequencing and microarray approaches to interrogate genetic variation, chromatin modifications, mRNA expression, and DNA methylation. In association with the post-doctoral molecular biologists in Dr.

Karin B. Michels

Dr. Michels has expertise in epidemiologic methods, and epigenetic, nutritional, and cancer epidemiology. Her research focuses on women's health. 

Dr. Michels is one of the co-founders of the area of epigenetic epidemiology and has made seminal contributions to the methods used in this field. Her research addresses the role of epigenetics in the developmental origins of health and disease (DOHaD). The Michels' lab studies the impact of events during perinatal life on the establishment of the epigenome.

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