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Robert Schiestl

Professor of Pathology and Environmental Health Sciences

Departments

DepartmentsType of Faculty
Environmental Health SciencesJoint Appointment
Contact Information
Phone: 
310.267.2087 (office)/ 310. 267.2593 (lab)

UCLA Fielding School of Public Health
650 Charles E. Young Drive South, 71-295B CHS
Los Angeles, CA 90095

Dr. Schiestl received his Ph.D. in Biology and Genetics from the University of Vienna, Austria, in 1983. He is currently a Professor of Pathology, Environmental Health and Radiation Oncology. Previously, he served as Assistant and Associate Professor in the Department of Cancer Cell Biology at the Harvard School of Public Health. He is Director of the UCLA Center for Environmental Genomics and a current member of the UCLA Cancer Center, UCLA Center of Occupational and Environmental Health, UCLA Interdepartmental Program in Molecular Toxicology (Faculty Advisory Committee), and UCLA ACCESS Graduate Program steering committee. He is also a member of the Planning Committee for the Environmental Mutagen Society meeting as well as Chair and Speak at the Symposium on "Genetic Instability" which will be held on March 11-15, 2003 at Miami Beach, Florida.

Education: 
PhD, Biology and Genetics, University of Vienna, Austria
BS, Biology and Biochemistry, University of Vienna, Austria
Selected Publications: 

Hafer, K. Iwamoto, K. K. Scuric, Z. Schiestl, R. H. Adaptive response to gamma radiation in Mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res. 2007; 168(2): 168-74.

Reliene, R. Schiestl, R. H. Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice. J Nutr. 2007; 137(1 Suppl): 229S-232S.

Gietz, R. D. Schiestl, R. H. Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1): 1-4.

Gietz, R. D. Schiestl, R. H. High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1): 31-4.

Reliene, R. Bishop, A. J. Schiestl, R. H. Involvement of homologous recombination in carcinogenesis. Adv Genet. 2007; 58: 67-87.

Gietz, R. D. Schiestl, R. H. Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1): 38-41.

Gietz, R. D. Schiestl, R. H. Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1): 5-8.

Gietz, R. D. Schiestl, R. H. Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1): 5-8.

Reliene, R. Schiestl, R. H. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis. 2006; 27(2): 240-4.

Hafer, K. Scuric, Z. Iwamoto, K. S. Schiestl, R. H. Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res. 2006; 165(5): 616-20.

Ohnishi, K. Scuric, Z. Schiestl, R. H. Okamoto, N. Takahashi, A. Ohnishi, T. siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status. Radiat Res. 2006; 166(3): 454-62.

Sommers, C. H. Schiestl, R. H. 2-Dodecylcyclobutanone does not induce mutations in the Salmonella mutagenicity test or intrachromosomal recombination in Saccharomyces cerevisiae. J Food Prot. 2004; 67(6): 1293-8.

Brennan, R. J. Schiestl, R. H. Detecting carcinogens with the yeast DEL assay. Methods Mol Biol. 2004; 262: 111-24.

Zhu, J. Schiestl, R. H. Human topoisomerase I mediates illegitimate recombination leading to DNA insertion into the ribosomal DNA locus in Saccharomyces cerevisiae. Mol Genet Genomics. 2004; 271(3): 347-58.

Reliene, R. Bishop, A. J. Aubrecht, J. Schiestl, R. H. In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol. 2004; 262: 125-39.

Rugo, R. E. Schiestl, R. H. Increases in oxidative stress in the progeny of X-irradiated cells. Radiat Res. 2004; 162(4): 416-25.

Stone, H. B. Moulder, J. E. Coleman, C. N. Ang, K. K. Anscher, M. S. Barcellos-Hoff, M. H. Dynan, W. S. Fike, J. R. Grdina, D. J. Greenberger, J. S. Hauer-Jensen, M. Hill, R. P. Kolesnick, R. N. Macvittie, T. J. Marks, C. McBride, W. H. Metting, N. Pellmar, T. Purucker, M. Robbins, M. E. Schiestl, R. H. Seed, T. M. Tomaszewski, J. E. Travis, E. L. Wallner, P. E. Wolpert, M. Zaharevitz, D. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res. 2004; 162(6): 711-28.

Galli, A. Cervelli, T. Schiestl, R. H. Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae. Genetics. 2003; 164(1): 65-79.

Bishop, A. J. Schiestl, R. H. Role of homologous recombination in carcinogenesis. Exp Mol Pathol. 2003; 74(2): 94-105.

Chen, L. Huang, S. Lee, L. Davalos, A. Schiestl, R. H. Campisi, J. Oshima, J. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair. Aging Cell. 2003; 2(4): 191-9.

Wiesmuller, L. Ford, J. M. Schiestl, R. H. DNA Damage, Repair, and Diseases. J Biomed Biotechnol. 2002; 2(2): 45.

Bishop, A. J. Schiestl, R. H. Homologous Recombination and Its Role in Carcinogenesis. J Biomed Biotechnol. 2002; 2(2): 75-85.

Rugo, R. E. Secretan, M. B. Schiestl, R. H. X radiation causes a persistent induction of reactive oxygen species and a delayed reinduction of TP53 in normal human diploid fibroblasts. Radiat Res. 2002; 158(2): 210-9.

Davidson, J. F. Schiestl, R. H. Cytotoxic and genotoxic consequences of heat stress are dependent on the presence of oxygen in Saccharomyces cerevisiae. J Bacteriol. 2001; 183(15): 4580-7.

Davidson, J. F. Schiestl, R. H. Mitochondrial respiratory electron carriers are involved in oxidative stress during heat stress in Saccharomyces cerevisiae. Mol Cell Biol. 2001; 21(24): 8483-9.

Long, N. C. Suh, J. Morrow, J. D. Schiestl, R. H. Murthy, G. G. Brain, J. D. Frei, B. Ozone causes lipid peroxidation but little antioxidant depletion in exercising and nonexercising hamsters. J Appl Physiol. 2001; 91(4): 1694-700.

Brennan, R. J. Schiestl, R. H. Persistent genomic instability in the yeast Saccharomyces cerevisiae induced by ionizing radiation and DNA-damaging agents. Radiat Res. 2001; 155(6): 768-77.

Bishop, A. J. Kosaras, B. Carls, N. Sidman, R. L. Schiestl, R. H. Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice. Carcinogenesis. 2001; 22(4): 641-9.

Kiechle, M. Friedl, A. A. Manivasakam, P. Eckardt-Schupp, F. Schiestl, R. H. DNA integration by Ty integrase in yku70 mutant Saccharomyces cerevisiae cells. Mol Cell Biol. 2000; 20(23): 8836-44.

Bishop, A. J. Schiestl, R. H. Homologous recombination as a mechanism for genome rearrangements: environmental and genetic effects. Hum Mol Genet. 2000; 9(16): 2427-334.

Davidson, J. F. Schiestl, R. H. Mis-targeting of multiple gene disruption constructs containing hisG. Curr Genet. 2000; 38(4): 188-90.

Carls, N. Schiestl, R. H. Effect of ionizing radiation on transgenerational appearance of p(un) reversions in mice. Carcinogenesis. 1999; 20(12): 2351-4.

Aubrecht, J. Secretan, M. B. Bishop, A. J. Schiestl, R. H. Involvement of p53 in X-ray induced intrachromosomal recombination in mice. Carcinogenesis. 1999; 20(12): 2229-36.

Galli, A. Schiestl, R. H. Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells. Genetics. 1998; 149(3): 1235-50.

Bonatti, S. Simili, M. Galli, A. Bagnato, P. Pigullo, S. Schiestl, R. H. Abbondandolo, A. Inhibition of the Mr 70,000 S6 kinase pathway by rapamycin results in chromosome malsegregation in yeast and mammalian cells. Chromosoma. 1998; 107(6-7): 498-506.

Manivasakam, P. Schiestl, R. H. Nonhomologous end joining during restriction enzyme-mediated DNA integration in Saccharomyces cerevisiae. Mol Cell Biol. 1998; 18(3): 1736-45.

Galli, A. Schiestl, R. H. Yeast strains to detect genomic deletions induced by carcinogens in cell-cycle arrested cells. Biotherapy. 1998; 11(2-3): 129-33.

Brennan, R. J. Schiestl, R. H. Aniline and its metabolites generate free radicals in yeast. Mutagenesis. 1997; 12(4): 215-20.

Aubrecht, J. Goad, M. E. Simpson, E. M. Schiestl, R. H. Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo. J Pharmacol Exp Ther. 1997; 281(2): 992-7.

Aubrecht, J. Goad, M. E. Schiestl, R. H. Tissue specific toxicities of the anticancer drug 6-thioguanine is dependent on the Hprt status in transgenic mice. J Pharmacol Exp Ther. 1997; 282(2): 1102-8.

Zhu, J. Schiestl, R. H. Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol. 1996; 16(4): 1805-12.

Aubrecht, J. Rugo, R. Schiestl, R. H. Carcinogens induce intrachromosomal recombination in human cells. Carcinogenesis. 1995; 16(11): 2841-6.

Yan, Y. X. Schiestl, R. H. Prakash, L. Mating-type suppression of the DNA-repair defect of the yeast rad6 delta mutation requires the activity of genes in the RAD52 epistasis group. Curr Genet. 1995; 28(1): 12-8.

Yap, W. Y. Schiestl, R. H. Nature of abortive transformation in Saccharomyces cerevisiae. Curr Genet. 1995; 28(6): 517-20.

Galli, A. Schiestl, R. H. Salmonella test positive and negative carcinogens show different effects on intrachromosomal recombination in G2 cell cycle arrested yeast cells. Carcinogenesis. 1995; 16(3): 659-63.

Schiestl, R. H. Zhu, J. Petes, T. D. Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol. 1994; 14(7): 4493-500.

Carls, N. Schiestl, R. H. Evaluation of the yeast DEL assay with 10 compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens. Mutat Res. 1994; 320(4): 293-303.

Schiestl, R. H. Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. Environ Health Perspect. 1993; 101 Suppl 5: 179-84.

Schiestl, R. H. Dominska, M. Petes, T. D. Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. Mol Cell Biol. 1993; 13(5): 2697-705.

Gietz, R. D. Schiestl, R. H. Applications of high efficiency lithium acetate transformation of intact yeast cells using single-stranded nucleic acids as carrier. Yeast. 1991; 7(3): 253-63.

Schiestl, R. H. Reddy, J. K. Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast. Carcinogenesis. 1990; 11(1): 173-6.

Schiestl, R. H. Gietz, R. D. Hastings, P. J. Wintersberger, U. Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae. Mol Gen Genet. 1990; 222(1): 25-32.

Schiestl, R. H. Prakash, S. RAD10, an excision repair gene of Saccharomyces cerevisiae, is involved in the RAD1 pathway of mitotic recombination. Mol Cell Biol. 1990; 10(6): 2485-91.

Schiestl, R. H. Prakash, S. Prakash, L. The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathway. Genetics. 1990; 124(4): 817-31.

Schiestl, R. H. Gietz, R. D. Mehta, R. D. Hastings, P. J. Carcinogens induce intrachromosomal recombination in yeast. Carcinogenesis. 1989; 10(8): 1445-55.

Schiestl, R. H. Reynolds, P. Prakash, S. Prakash, L. Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage. Mol Cell Biol. 1989; 9(5): 1882-96.

Schiestl, R. H. DNA-damaging agents show different kinetics in induction of heterothallic mating-type switching during growth after treatment in yeast. Mutat Res. 1989; 227(4): 269-74.

Schiestl, R. H. Gietz, R. D. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet. 1989; 16(5-6): 339-46.

Schiestl, R. H. Prakash, S. Interactions of the RAD7 and RAD23 excision repair genes of Saccharomyces cerevisiae with DNA repair genes in different epistasis groups. Curr Genet. 1989; 16(4): 219-23.

Schiestl, R. H. Chan, W. S. Gietz, R. D. Mehta, R. D. Hastings, P. J. Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast. Mutat Res. 1989; 224(4): 427-36.

Schiestl, R. H. Igarashi, S. Hastings, P. J. Analysis of the mechanism for reversion of a disrupted gene. Genetics. 1988; 119(2): 237-47.

Schiestl, R. H. Prakash, S. RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol Cell Biol. 1988; 8(9): 3619-26.

Schiestl, R. Wintersberger, U. Induction of mating type interconversion in a heterothallic strain of Saccharomyces cerevisiae by DNA damaging agents. Mol Gen Genet. 1983; 191(1): 59-65.

Schiestl, R. Wintersberger, U. X-ray enhances mating type switching in heterothallic strains of Saccharomyces cerevisiae. Mol Gen Genet. 1982; 186(4): 512-7.

Ku, W. W. Aubrecht, J. Mauthe, R. J. Schiestl, R. H. Fornace, A. J., Jr. Why Not Start With a Single Test: A Transformational Alternative to Genotoxicity Hazard and Risk Assessment. Toxicol Sci. 2007; .

Ohnishi, K. Scuric, Z. Yau, D. Schiestl, R. H. Okamoto, N. Takahashi, A. Ohnishi, T. Heat-induced phosphorylation of NBS1 in human skin fibroblast cells. J Cell Biochem. 2006; 99(6): 1642-50.

Reliene, R. Goad, M. E. Schiestl, R. H. Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair (Amst). 2006; 5(11): 1392-7.

Reliene, R. Schiestl, R. H. Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst). 2006; 5(7): 852-9.

Reliene, R. Schiestl, R. H. Differences in animal housing facilities and diet may affect study outcomes-a plea for inclusion of such information in publications. DNA Repair (Amst). 2006; 5(6): 651-3.

Kirpnick-Sobol, Z. Reliene, R. Schiestl, R. H. Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice. Cancer Res. 2006; 66(7): 3480-4.

Howlett, N. G. Scuric, Z. D'Andrea, A. D. Schiestl, R. H. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. DNA Repair (Amst). 2006; 5(2): 251-7.

Sommers, C. H. Schiestl, R. H. Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae. Mutat Res. 2006; 593(1-2): 1-8.

Bishop, A. J. Kosaras, B. Hollander, M. C. Fornace, A., Jr. Sidman, R. L. Schiestl, R. H. p21 controls patterning but not homologous recombination in RPE development. DNA Repair (Amst). 2006; 5(1): 111-20.

Kirpnick, Z. Homiski, M. Rubitski, E. Repnevskaya, M. Howlett, N. Aubrecht, J. Schiestl, R. H. Yeast DEL assay detects clastogens. Mutat Res. 2005; 582(1-2): 116-34.

Reliene, R. Hlavacova, A. Mahadevan, B. Baird, W. M. Schiestl, R. H. Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice. Mutat Res. 2005; 570(2): 245-52.

Egorov, A. I. Howlett, N. G. Schiestl, R. H. Mutagen X and chlorinated tap water are recombinagenic in yeast. Mutat Res. 2004; 563(2): 159-69.

Secretan, M. B. Scuric, Z. Oshima, J. Bishop, A. J. Howlett, N. G. Yau, D. Schiestl, R. H. Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay. Mutat Res. 2004; 554(1-2): 351-64.

Reliene, R. Fischer, E. Schiestl, R. H. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res. 2004; 64(15): 5148-53.

Reliene, R. Bishop, A. J. Li, G. Schiestl, R. H. Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst). 2004; 3(2): 103-11.

Howlett, N. G. Schiestl, R. H. Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae. DNA Repair (Amst). 2004; 3(2): 127-34.

Reliene, R. Schiestl, R. H. Mouse models for induced genetic instability at endogenous loci. Oncogene. 2003; 22(45): 7000-10.

Storer, R. D. French, J. E. Donehower, L. A. Gulezian, D. Mitsumori, K. Recio, L. Schiestl, R. H. Sistare, F. D. Tamaoki, N. Usui, T. van Steeg, H. Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines. Mutat Res. 2003; 540(2): 165-76.

Bishop, A. J. Hollander, M. C. Kosaras, B. Sidman, R. L. Fornace, A. J., Jr. Schiestl, R. H. Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res. 2003; 63(17): 5335-43.

Kiechle, M. Manivasakam, P. Eckardt-Schupp, F. Schiestl, R. H. Friedl, A. A. Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion. Nucleic Acids Res. 2002; 30(24): e136.

Vonarx, E. J. Howlett, N. G. Schiestl, R. H. Kunz, B. A. Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant. Gene. 2002; 296(1-2): 1-9.

Oshima, J. Huang, S. Pae, C. Campisi, J. Schiestl, R. H. Lack of WRN results in extensive deletion at nonhomologous joining ends. Cancer Res. 2002; 62(2): 547-51.

Manivasakam, P. Aubrecht, J. Sidhom, S. Schiestl, R. H. Restriction enzymes increase efficiencies of illegitimate DNA integration but decrease homologous integration in mammalian cells. Nucleic Acids Res. 2001; 29(23): 4826-33.

Bishop, A. J. Schiestl, R. H. Homologous recombination as a mechanism of carcinogenesis. Biochim Biophys Acta. 2001; 1471(3): M109-21.

Bishop, A. J. Kosaras, B. Sidman, R. L. Schiestl, R. H. Benzo(a)pyrene and X-rays induce reversions of the pink-eyed unstable mutation in the retinal pigment epithelium of mice. Mutat Res. 2000; 457(1-2): 31-40.

Howlett, N. G. Schiestl, R. H. Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay. Mutat Res. 2000; 454(1-2): 53-62.

Bishop, A. J. Barlow, C. Wynshaw-Boris, A. J. Schiestl, R. H. Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice. Cancer Res. 2000; 60(2): 395-9.

Brennan, R. J. Schiestl, R. H. The aromatic amine carcinogens o-toluidine and o-anisidine induce free radicals and intrachromosomal recombination in Saccharomyces cerevisiae. Mutat Res. 1999; 430(1): 37-45.

Galli, A. Schiestl, R. H. Cell division transforms mutagenic lesions into deletion-recombinagenic lesions in yeast cells. Mutat Res. 1999; 429(1): 13-26.

Galli, A. Schiestl, R. H. Effect of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in S-phase arrested yeast cells. Mutat Res. 1998; 419(1-3): 53-68.

Brennan, R. J. Schiestl, R. H. Positive responses to carcinogens in the yeast DEL recombination assay are not due to selection of preexisting spontaneous revertants. Mutat Res. 1998; 421(1): 117-20.

Brennan, R. J. Schiestl, R. H. Free radicals generated in yeast by the Salmonella test-negative carcinogens benzene, urethane, thiourea and auramine O. Mutat Res. 1998; 403(1-2): 65-73.

Jalili, T. Murthy, G. G. Schiestl, R. H. Cigarette smoke induces DNA deletions in the mouse embryo. Cancer Res. 1998; 58(12): 2633-8.

Brennan, R. J. Schiestl, R. H. Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae. Mutat Res. 1998; 397(2): 271-8.

Schiestl, R. H. Aubrecht, J. Yap, W. Y. Kandikonda, S. Sidhom, S. Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin induce intrachromosomal recombination in vitro and in vivo. Cancer Res. 1997; 57(19): 4378-83.

Schiestl, R. H. Aubrecht, J. Khogali, F. Carls, N. Carcinogens induce reversion of the mouse pink-eyed unstable mutation. Proc Natl Acad Sci U S A. 1997; 94(9): 4576-81.

Galli, A. Schiestl, R. H. Effects of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in G1-arrested yeast cells. Mutat Res. 1996; 370(3-4): 209-21.

Brennan, R. J. Schiestl, R. H. Cadmium is an inducer of oxidative stress in yeast. Mutat Res. 1996; 356(2): 171-8.

Brennan, R. J. Kandikonda, S. Khrimian, A. P. DeMilo, A. B. Liquido, N. J. Schiestl, R. H. Saturated and monofluoro analogs of the oriental fruit fly attractant methyl eugenol show reduced genotoxic activities in yeast. Mutat Res. 1996; 369(3-4): 175-81.

Galli, A. Schiestl, R. H. Hydroxyurea induces recombination in dividing but not in G1 or G2 cell cycle arrested yeast cells. Mutat Res. 1996; 354(1): 69-75.

Aubrecht, J. Manivasakam, P. Schiestl, R. H. Controlled gene expression in mammalian cells via a regulatory cascade involving the tetracycline transactivator and lac repressor. Gene. 1996; 172(2): 227-31.

Davidson, J. F. Whyte, B. Bissinger, P. H. Schiestl, R. H. Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1996; 93(10): 5116-21.

Galli, A. Schiestl, R. H. On the mechanism of UV and gamma-ray-induced intrachromosomal recombination in yeast cells synchronized in different stages of the cell cycle. Mol Gen Genet. 1995; 248(3): 301-10.

Manivasakam, P. Weber, S. C. McElver, J. Schiestl, R. H. Micro-homology mediated PCR targeting in Saccharomyces cerevisiae. Nucleic Acids Res. 1995; 23(14): 2799-800.

Gietz, R. D. Schiestl, R. H. Willems, A. R. Woods, R. A. Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast. 1995; 11(4): 355-60.

Schiestl, R. H. Khogali, F. Carls, N. Reversion of the mouse pink-eyed unstable mutation induced by low doses of x-rays. Science. 1994; 266(5190): 1573-6.

Brennan, R. J. Swoboda, B. E. Schiestl, R. H. Oxidative mutagens induce intrachromosomal recombination in yeast. Mutat Res. 1994; 308(2): 159-67.

Manivasakam, P. Schiestl, R. H. High efficiency transformation of Saccharomyces cerevisiae by electroporation. Nucleic Acids Res. 1993; 21(18): 4414-5.

Schiestl, R. H. Wintersberger, U. DNA damage induced mating type switching in Saccharomyces cerevisiae. Mutat Res. 1992; 284(1): 111-23.

Gietz, D. St Jean, A. Woods, R. A. Schiestl, R. H. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 1992; 20(6): 1425.

Schiestl, R. H. Petes, T. D. Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1991; 88(17): 7585-9.

Schiestl, R. H. Nonmutagenic carcinogens induce intrachromosomal recombination in yeast. Nature. 1989; 337(6204): 285-8.