Nicole Green

Dr. Green is the Director of the Los Angeles County Public Health Laboratory. She is an accomplished scientist with more than 15 years of experience working in the field of Microbiology. Her training includes molecular biology, bacterial pathogenesis mechanisms, molecular epidemiological surveillance studies, and design of laboratory developed tests. The majority of her projects have combined the use of epidemiological data with state-of-the-art laboratory technology such as PCR and DNA sequencing to study large numbers of clinical isolates. She came to Public Health because it represented an opportunity for her to integrate techniques and technology that she learned from scientific research to improve community health and patient outcome as well as fulfill the need for qualified Public Health Laboratory Directors.  She is a licensed California Public Health Microbiologist and also holds national certification through the American Society for Clinical Pathology and State of California as a clinical microbiologist. Dr. Green is board certified as a medical microbiologist through the American Board of Medical Microbiology. 

She is passionate about teaching and is dedicated to developing new public health and clinical microbiology professionals. Her most important accomplishment has been to share the knowledge she has learned from her experiences and continue the public health microbiologist training program which serves as a pipeline for public health workforce development and future laboratory professionals. 

She has served on a number of committees for the Los Angeles County Department of Public Health including the Public Health Emergency Response Leadership Group, Tuberculosis Control Program Research Committee, Science Work Group, Division of HIV and STD Programs 2nd District laboratory representative, CDC Region IX Infertility Prevention Program laboratory representative. She has also served on the UCLA Committee on Postdoctoral Education Program (CPEP), UCLA Institutional Biosafety Committee, American Society for Pathology Microbiology workgroup, Association of Public Health Laboratories Culture Independent Diagnostic Test workgroup, California Association of Public Health Laboratory Directors Training Committee, and several conference and workshop planning committees. 

Dr. Green is an active member of the American Society for Microbiology, Southern California American Society for Microbiology, American Biological Safety Association, California Association for Medical Laboratory Technology, and the Association of Public Health Laboratories. 

Areas of Interest

Molecular Epidemiology, Evaluation of Diagnostic Methods, Comparative Genomics, Public Health Workforce Development. 

Selected Publications

• Pannaraj PS, Wang H, Rivas H, Wiryawan H, Smit M, Green N, Aldrovandi GM, El Amin AN, and Mascola L. 2014. School-located influenza vaccination decreases laboratory-confirmed influenza and improves school attendance. Clin. Infect. Dis. May 14. pii: ciu340. Epub ahead of print. 
• Abbott SL, Moler S, Green N, Tran RK, Wainwright K, and Janda JM. 2011. Clinical and laboratory diagnostic characteristics and cytotoxigenic potential of Hafnia alvei and Hafnia paralvei strains. J. Clin. Micro. 49:3122-3126. 
• Sitkiewicz I, Green NM, Guo N, Mereghetti L, Musser JM. 2011. Lateral gene transfer of streptococcal ICE element RD2 (region of difference 2) encoding secreted proteins. BMC Microbiol. 11:65.  
• Green NM and Janda JM. 2010. Clin. Micro. News. The clinical microbiologist’s molecular toolbox: an ever-expanding resource for bacterial identification in the laboratory. 32:151-160.  
• Sitkiewicz I, Green NM, Guo N, Bongiovanni AM, Witkin SS, and Musser JM. 2010. Adaptation of group A Streptococcus to human amniotic fluid. PLoS ONE. 5(3):e9785. 
• Olsen RJ, Sitkiewicz I, Ayeras AA, Gonulal VE, Cantu C, Beres SB, Green NM, Lei B, Humbird T, Greaver J, Chang E, Ragasa WP, Montgomery CA, Cartwright J Jr, McGeer A, Low DE, Whitney AR, Cagle PT, Blasdel TL, DeLeo FR, and Musser JM. 2010. Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axis. Proc. Natl. Acad. Sci. U S A. 107:888-93. 
• Mereghetti L, Sitkiewicz I, Green NM, and Musser JM. 2009. Identification of an unusual pattern of global gene expression in group B Streptococcus grown in human blood. PLoS ONE. 4:e7145.  
• Green NM, Tran R, and Janda JM. 2009. Klebsiella and gastrointestinal symptoms with particular emphasis on Klebsiella oxytoca antibiotic-associated colitis. Clin. Micro. News. 31: 111-116. 
• Sitkiewicz I, Green NM, Guo N, Bongiovanni AM, Witkin SS, and Musser JM. 2009. Transcriptome adaptation of group B Streptococcus to growth in human amniotic fluid. PLoS ONE. 4:e6114. 
• Mereghetti L, Sitkiewicz I, Green NM, and Musser JM. 2008. Remodeling of the Streptococcus agalactiae transcriptome in response to growth temperature. PLoS ONE.  3:e2785. 
• Mereghetti L, Sitkiewicz I, Green NM, and Musser JM. 2008. Extensive adaptive changes occur in the transcriptome of Streptococcus agalactiae (group B Streptococcus) in response to incubation with human blood. PLoS ONE. 3:e3143. 
• Zhang S, Green NM, Sitkiewicz I, LeFebvre RB, and Musser JM. 2006. Identification and characterization of an antigen I/II family protein produced by group A Streptococcus. Infect. Immun. 74:4200-13. 
• Green NM, Beres SB, Graviss EA, Allison JE, McGeer AJ, Vuopio-Varkila J, LeFebvre RB, and Musser JM. 2005.  Genetic diversity among type emm28 group A Streptococcus strains causing invasive infections and pharyngitis. J. Infect. Dis. 192:760-70. 
• Green NM, Zhang S, Porcella SF, Nageic MJ, Barbian KD, Beres SB, LeFebvre RB, and Musser JM. 2005. Genome sequence of a serotype M28 strain of group A Streptococcus: new insights into puerperal sepsis and bacterial disease specificity. J. Clin. Microbiol. 43:4083-91.   
• Reid SD, Montgomery AG, Voyich JM, DeLeo FR, Lei B, Ireland RM, Green NM, Liu M, Lukomski S, and Musser JM.  2003. Characterization of an extracellular virulence factor made by group A Streptococcus with homology to the Listeria monocytogenes internalin family of proteins. Infect. Immun.  71:7043-52.